Hierarchically aligned fibrillar fibrin hydrogel designed for spinal cord injury repair
نویسندگان
چکیده
منابع مشابه
Effect of hierarchically aligned fibrin hydrogel in regeneration of spinal cord injury demonstrated by tractography: A pilot study
Some studies have reported that scaffold or cell-based transplantation may improve functional recovery following SCI, but no imaging information regarding regeneration has been provided to date. This study used tractography to show the regenerating process induced by a new biomaterial-aligned fibrin hydrogel (AFG). A total of eight canines subjected to SCI procedures were assigned to the contro...
متن کاملStem cell derived radial glial cells in magnetically aligned scaffold for repair after spinal cord injury
strategies have not been successful in promoting robust functional recovery following spinal cord injury (SCI). Part of the reason why cell transplant therapies have failed may be related to improper targeting of regenerating axons through the lesion. In this report, we propose a novel therapeutic approach using stem cell-derived radial glial cells in combination with a magnetically aligned fib...
متن کاملP7: Current Status of Fibrin-Based Scaffolds in the Treatment of Spinal Cord Injury
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملRepair of chronic spinal cord injury.
Advances in medical and rehabilitative care now allow the 10-12,000 individuals who suffer spinal cord injuries each year in the United States to lead productive lives of nearly normal life expectancy, so that the numbers of those with chronic injuries will approximate 300,000 at the end of the next decade. This signals an urgent need for new treatments that will improve repair and recovery aft...
متن کاملCurrent trends in spinal cord injury repair.
One of the rapidly prevailing neurological disorders affecting thousands of people per year is spinal cord injury (SCI). Though, great research has been made in recent past to understand thoroughly the molecular bases of the diseases, no fully restorative treatments for SCI are available. However, various rehabilitative, cellular and molecular therapies are being tested in animal models. Some o...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.01340